Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.

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Title: Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.
Authors: Martin, Nikolas T.1,2 (AUTHOR), Crupi, Mathieu J. F.1,2 (AUTHOR), Taha, Zaid1,2 (AUTHOR), Poutou, Joanna1,2 (AUTHOR), Whelan, Jack T.1,2 (AUTHOR), Vallati, Sydney1,2 (AUTHOR), Petryk, Julia1 (AUTHOR), Marius, Ricardo1 (AUTHOR), Austin, Bradley1 (AUTHOR), Azad, Taha1,2 (AUTHOR), Boulanger, Mason1 (AUTHOR), Burgess, Tamara1 (AUTHOR), Sanders, Ilson1 (AUTHOR), Victoor, Camille1 (AUTHOR), Dickinson, Bryan C.3 (AUTHOR), Diallo, Jean-Simon1,2 (AUTHOR), Ilkow, Carolina S.1,2 (AUTHOR), Bell, John C.1,2 (AUTHOR) jbell@ohri.ca
Source: Pharmaceuticals (14248247). May2023, Vol. 16 Issue 5, p709. 23p.
Database: Academic Search Ultimate
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ISSN:14248247
DOI:10.3390/ph16050709