Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load.
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| Title: | Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load. |
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| Authors: | Cody, Jonathan W.1 (AUTHOR), Ellis-Connell, Amy L.2 (AUTHOR), O'Connor, Shelby L.2 (AUTHOR), Pienaar, Elsje1,3 (AUTHOR) epienaar@purdue.edu |
| Source: | PLoS Computational Biology. 8/24/2023, Vol. 19 Issue 8, p1-25. 25p. 4 Charts, 5 Graphs. |
| Database: | Academic Search Ultimate |
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| ISSN: | 1553734X |
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| DOI: | 10.1371/journal.pcbi.1011425 |
