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Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance.

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Bibliographic Details
Title: Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance.
Authors: Gjuka, Donjeta1 (AUTHOR), Adib, Elio1,2,3 (AUTHOR), Garrison, Kendra1 (AUTHOR), Chen, Jianfeng4 (AUTHOR), Zhang, Yuxue4 (AUTHOR), Li, Wenjiao4 (AUTHOR), Boutz, Daniel5 (AUTHOR), Lamb, Candice1,5 (AUTHOR), Tanno, Yuri1 (AUTHOR), Nassar, Amin6 (AUTHOR), El Zarif, Talal3 (AUTHOR), Kale, Neil7 (AUTHOR), Rakaee, Mehrdad2 (AUTHOR), Mouhieddine, Tarek H.8 (AUTHOR), Alaiwi, Sarah Abou2,3 (AUTHOR), Gusev, Alexander9,10 (AUTHOR), Rogers, Thomas11 (AUTHOR), Gao, Jianjun4 (AUTHOR), Georgiou, George1,5,12,13 (AUTHOR), Kwiatkowski, David J.1,2 (AUTHOR) dk@rics.bwh.harvard.edu
Source: Cancer Cell. Oct2023, Vol. 41 Issue 10, p1774-1774. 1p.
Database: Academic Search Ultimate
Description
ISSN:15356108
DOI:10.1016/j.ccell.2023.09.005