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Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity.

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Title: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity.
Authors: Tsai, Tien-Ying1,2,3 (AUTHOR), Chen, Chun-Yu1 (AUTHOR), Lin, Tien-Wei1 (AUTHOR), Lin, Tien-Chang4,5 (AUTHOR), Chiu, Feng-Lan6 (AUTHOR), Shih, Orion4 (AUTHOR), Chang, Ming-Yun1,7 (AUTHOR), Lin, Yu-Chun1 (AUTHOR), Su, An-Chung5 (AUTHOR), Chen, Chiung-Mei8 (AUTHOR), Jeng, U-Ser4,5 (AUTHOR), Kuo, Hung-Chih6 (AUTHOR), Chang, Chi-Fon1 (AUTHOR), Chen, Yun-Ru1 (AUTHOR) yrchen@gate.sinica.edu.tw
Source: Communications Biology. 10/9/2023, Vol. 6 Issue 1, p1-16. 16p.
Database: Academic Search Ultimate
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ISSN:23993642
DOI:10.1038/s42003-023-05142-0