Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.

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Title: Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
Authors: Bennett, Craig L.1,2 (AUTHOR), Dastidar, Somasish2,3 (AUTHOR), Arnold, Frederick J.1 (AUTHOR), McKinstry, Spencer U.2 (AUTHOR), Stockford, Cameron1 (AUTHOR), Freibaum, Brian D.4 (AUTHOR), Sopher, Bryce L.5 (AUTHOR), Wu, Meilin6 (AUTHOR), Seidner, Glen6 (AUTHOR), Joiner, William5 (AUTHOR), Taylor, J. Paul4,7 (AUTHOR), West, Ryan J. H.8,9 (AUTHOR) r.j.west@sheffield.ac.uk, La Spada, Albert R.1,2,10,11 (AUTHOR) alaspada@uci.edu
Source: Acta Neuropathologica Communications. 10/17/2023, Vol. 11 Issue 1, p1-18. 18p.
Database: Academic Search Ultimate
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ISSN:20515960
DOI:10.1186/s40478-023-01665-z