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The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.

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Title: The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
Authors: Kimani, Serah W.1,2 (AUTHOR), Perveen, Sumera1 (AUTHOR), Szewezyk, Magdalena1 (AUTHOR), Zeng, Hong1 (AUTHOR), Dong, Aiping1 (AUTHOR), Li, Fengling1 (AUTHOR), Ghiabi, Pegah1 (AUTHOR), Li, Yanjun1 (AUTHOR), Chau, Irene1 (AUTHOR), Arrowsmith, Cheryl H.1,2,3 (AUTHOR), Barsyte-Lovejoy, Dalia1,4 (AUTHOR), Santhakumar, Vijayaratnam1 (AUTHOR) santha.santhakumar@utoronto.ca, Vedadi, Masoud4,5 (AUTHOR), Halabelian, Levon1,4 (AUTHOR) l.halabelian@utoronto.ca
Source: Communications Biology. 12/16/2023, Vol. 6 Issue 1, p1-10. 10p.
Database: Academic Search Ultimate
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ISSN:23993642
DOI:10.1038/s42003-023-05655-8