The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation.

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Title: The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation.
Authors: Totland, Max Zachrisson1 (AUTHOR), Knudsen, Lars Mørland1 (AUTHOR), Rasmussen, Nikoline Lander1,2 (AUTHOR), Omori, Yasufumi3 (AUTHOR), Sørensen, Vigdis4,5 (AUTHOR), Elster, Vilde C. Wivestad1 (AUTHOR), Stenersen, Jakob Mørkved1 (AUTHOR), Larsen, Mathias1 (AUTHOR), Jensen, Caroline Lunder1 (AUTHOR), Zickfeldt Lade, Anna A.1 (AUTHOR), Bruusgaard, Emilie1 (AUTHOR), Basing, Sebastian1 (AUTHOR), Kryeziu, Kushtrim1 (AUTHOR), Brech, Andreas4,6,7 (AUTHOR), Aasen, Trond8 (AUTHOR), Lothe, Ragnhild A.1,7,9 (AUTHOR), Leithe, Edward1 (AUTHOR)
Source: Cellular & Molecular Life Sciences. Jan2024, Vol. 81 Issue 1, p1-20. 20p.
Database: Academic Search Ultimate
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ISSN:1420682X
DOI:10.1007/s00018-024-05165-8