Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.
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| Title: | Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate. |
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| Authors: | Rouleau, Francois D.1,2,3,4 (AUTHOR) Francois.rouleau.2@ulaval.ca, Dubé, Alexandre K.1,2,3,5 (AUTHOR), Gagnon-Arsenault, Isabelle1,2,3,5 (AUTHOR), Dibyachintan, Soham1,2,3,4 (AUTHOR), Pageau, Alicia1,2,3,4 (AUTHOR), Després, Philippe C.1,2,3,4 (AUTHOR), Lagüe, Patrick1,2,3,4 (AUTHOR), Landry, Christian R.1,2,3,4,5 (AUTHOR) |
| Source: | PLoS Genetics. 4/29/2024, Vol. 20 Issue 4, p1-29. 29p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 15537390 |
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| DOI: | 10.1371/journal.pgen.1011252 |
