Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.

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Title: Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
Authors: Ortiz, Camila1,2 (AUTHOR) cortiz@roskampinstitute.org, Pearson, Andrew1,2 (AUTHOR), McCartan, Robyn1 (AUTHOR), Roche, Shawn1 (AUTHOR), Carothers, Nolan1 (AUTHOR), Browning, Mackenzie1 (AUTHOR), Perez, Sylvia3 (AUTHOR), He, Bin3 (AUTHOR), Ginsberg, Stephen D.4,5 (AUTHOR), Mullan, Michael1 (AUTHOR), Mufson, Elliott J.3 (AUTHOR), Crawford, Fiona1,2,6 (AUTHOR), Ojo, Joseph1,2 (AUTHOR)
Source: Journal of Neuroinflammation. 5/15/2024, Vol. 21 Issue 1, p1-24. 24p.
Database: Academic Search Ultimate
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Description
ISSN:17422094
DOI:10.1186/s12974-024-03117-4