Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody.
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| Title: | Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody. |
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| Authors: | Jungholm, Oscar1, Trkulja, Carolina2,3, Moche, Martin4, Srinivasa, Sreesha P.2,5, Christakopoulou, Maria-Nefeli1, Davidson, Max2, Reymer, Anna2,6, Jardemark, Kent1, Fogaça, Rafaela Lenza2, Ashok, Anaswara2, Jeffries, Gavin3, Ampah-Korsah, Henry4, Strandback, Emilia4, Andréll, Juni4, Nyman, Tomas4, Nouairia, Ghada7, Orwar, Owe1,2 owe.orwar@ki.se |
| Source: | Scientific Reports. 8/23/2024, Vol. 14 Issue 1, p1-13. 13p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-024-70217-9 |