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Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.

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Title: Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.
Authors: Lessard, Samuel1,2 (AUTHOR) samuel.lessard@sanofi.com, Rimmelé, Pauline1 (AUTHOR), Ling, Hui1 (AUTHOR), Moran, Kevin1 (AUTHOR), Vieira, Benjamin1 (AUTHOR), Lin, Yi-Dong1 (AUTHOR), Rajani, Gaurav Manohar1 (AUTHOR), Hong, Vu1 (AUTHOR), Reik, Andreas3 (AUTHOR), Boismenu, Richard3 (AUTHOR), Hsu, Ben3 (AUTHOR), Chen, Michael3 (AUTHOR), Cockroft, Bettina M.3 (AUTHOR), Uchida, Naoya4 (AUTHOR), Tisdale, John4 (AUTHOR), Alavi, Asif5 (AUTHOR), Krishnamurti, Lakshmanan6 (AUTHOR), Abedi, Mehrdad7 (AUTHOR), Galeon, Isobelle1 (AUTHOR), Reiner, David1 (AUTHOR)
Source: Scientific Reports. 10/16/2024, Vol. 14 Issue 1, p1-18. 18p.
Database: Academic Search Ultimate
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ISSN:20452322
DOI:10.1038/s41598-024-74716-7