Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria.

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Title: Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria.
Authors: Abd-Rahman, Azrin N.1 (AUTHOR), Kaschek, Daniel2 (AUTHOR), Kümmel, Anne2 (AUTHOR), Webster, Rebecca1 (AUTHOR), Potter, Adam J.1 (AUTHOR), Odedra, Anand1,3 (AUTHOR), Woolley, Stephen D.1,4 (AUTHOR), Llewellyn, Stacey1 (AUTHOR), Webb, Lachlan1 (AUTHOR), Marquart, Louise1,5 (AUTHOR), Chalon, Stephan6 (AUTHOR), Gaaloul, Myriam El6 (AUTHOR), McCarthy, James S.1,7 (AUTHOR), Möhrle, Jörg J.6,8,9 (AUTHOR) joerg.moehrle@unibas.ch, Barber, Bridget E.1,10 (AUTHOR)
Source: BMC Medicine. 11/28/2024, Vol. 22 Issue 1, p1-14. 14p.
Database: Academic Search Ultimate
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ISSN:17417015
DOI:10.1186/s12916-024-03787-0