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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses.

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Title: A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses.
Authors: Van Loy, Benjamin1 (AUTHOR), Pujol, Eugènia2,3 (AUTHOR), Kamata, Kenichi4 (AUTHOR), Lee, Xiao Yin4 (AUTHOR), Bakirtzoglou, Nikolai1 (AUTHOR), Van Berwaer, Ria1 (AUTHOR), Vandeput, Julie1 (AUTHOR), Mestdagh, Cato1 (AUTHOR), Persoons, Leentje1 (AUTHOR), De Wijngaert, Brent1 (AUTHOR), Goovaerts, Quinten1 (AUTHOR), Noppen, Sam1 (AUTHOR), Jacquemyn, Maarten1 (AUTHOR), Ahmadzadeh, Kourosh1 (AUTHOR), Bernaerts, Eline1 (AUTHOR), Martín-López, Juan2,3 (AUTHOR), Escriche, Celia2,3 (AUTHOR), Vanmechelen, Bert1 (AUTHOR), Krasniqi, Besir5 (AUTHOR), Singh, Abhimanyu K.1 (AUTHOR)
Source: PLoS Pathogens. 2/11/2025, Vol. 21 Issue 2, p1-32. 32p.
Database: Academic Search Ultimate
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Description
ISSN:15537366
DOI:10.1371/journal.ppat.1012571