Reducing PDK4 level constitutes a pivotal mechanism for glucocorticoids to impede osteoblastic differentiation through the enhancement of ferroptosis in mesenchymal stem cells.

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Title: Reducing PDK4 level constitutes a pivotal mechanism for glucocorticoids to impede osteoblastic differentiation through the enhancement of ferroptosis in mesenchymal stem cells.
Authors: Jiang, Yue1,2 (AUTHOR), Ye, Ai-Hua1,2 (AUTHOR), He, Wen-Ge2,3,4 (AUTHOR), Liu, Lu1,2 (AUTHOR), Gao, Xiang2,5 (AUTHOR), Liu, Hang2,5 (AUTHOR), Liu, Wen-Ting1,2 (AUTHOR), Ye, Fang-Lin1,2 (AUTHOR), He, Dong-Mei1,2 (AUTHOR), Liao, Jun-Yi3 (AUTHOR), Wang, Jing6 (AUTHOR) wjsy86@hospital.cqmu.edu.cn, He, Bai-Cheng1,2 (AUTHOR) bche@cqmu.edu.cn
Source: Stem Cell Research & Therapy. 2/25/2025, Vol. 16 Issue 1, p1-20. 20p.
Database: Academic Search Ultimate
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ISSN:17576512
DOI:10.1186/s13287-025-04186-9