Full sequencing of 100mer sgRNA via tandem mass spectrometry by targeted RNase H digestion with customized probes.

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Title: Full sequencing of 100mer sgRNA via tandem mass spectrometry by targeted RNase H digestion with customized probes.
Authors: Gawlig, Christopher1 (AUTHOR) gawlig@biospring.de, Hirschberger, Rebecca1 (AUTHOR) hirschberger@biospring.de, Hanci, Güngör1 (AUTHOR) hanci@biospring.de, Schott, Saskia1 (AUTHOR) schott@biospring.de, Marandi, Shima1 (AUTHOR) marandi@biospring.de, Hesse, Ida Ronja1 (AUTHOR) i.hesse@biospring.de, Rühl, Michael1 (AUTHOR) ruehl@biospring.de
Source: Analytical & Bioanalytical Chemistry. Mar2025, Vol. 417 Issue 8, p1497-1506. 10p.
Database: Academic Search Ultimate
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ISSN:16182642
DOI:10.1007/s00216-025-05737-y