Complement C3a promotes the formation of osteoclasts by inhibiting Sirt1 to activate the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma.

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Title: Complement C3a promotes the formation of osteoclasts by inhibiting Sirt1 to activate the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma.
Authors: Jiang, Fengjuan1,2,3 (AUTHOR), Zhang, Yunhe1,2,3 (AUTHOR), Peng, Fengping1,2,3 (AUTHOR), Liu, Hui1,2,3 (AUTHOR), Ding, Kai1,2,3 (AUTHOR), Cao, Panpan1,2,3 (AUTHOR), Liu, Xiaohan1,2,3 (AUTHOR), Li, Lijuan1,2,3 (AUTHOR), Liu, Zhaoyun1,2,3 (AUTHOR) liuzhaoyun114@163.com, Fu, Rong1,2,3 (AUTHOR) furong8369@tmu.edu.cn
Source: Journal of Translational Medicine. 3/16/2025, Vol. 23 Issue 1, p1-20. 20p.
Database: Academic Search Ultimate
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ISSN:14795876
DOI:10.1186/s12967-025-06319-3