A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody.
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| Title: | A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody. |
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| Authors: | Michelet, Robin1 (AUTHOR), Petersson, Klas2 (AUTHOR), Huisman, Marc C.3 (AUTHOR), Menke‐van der Houven van Oordt, C. Willemien4,5 (AUTHOR), Miedema, Iris H. C.4,5 (AUTHOR), Thiele, Andrea6 (AUTHOR), Montaseri, Ghazal6 (AUTHOR), Pérez‐Pitarch, Alejandro7 (AUTHOR), Busse, David7 (AUTHOR) david_maximilian.busse@boehringer‐ingelheim.com |
| Source: | CPT: Pharmacometrics & Systems Pharmacology. Mar2025, Vol. 14 Issue 3, p460-473. 14p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 21638306 |
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| DOI: | 10.1002/psp4.13285 |
