Is the GFR‐based scaling approach adequate for predicting pediatric renal clearance of drugs with passive tubular reabsorption? Insights from PBPK modeling.

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Title: Is the GFR‐based scaling approach adequate for predicting pediatric renal clearance of drugs with passive tubular reabsorption? Insights from PBPK modeling.
Authors: Li, Sanwang1,2,3 (AUTHOR), Ye, Xuexin1 (AUTHOR), Wang, Qiushi1 (AUTHOR), Cheng, Zeneng1 (AUTHOR), Liu, Feiyan1 (AUTHOR), Xie, Feifan1 (AUTHOR) feifan.xie@csu.edu.cn
Source: CPT: Pharmacometrics & Systems Pharmacology. Jan2025, Vol. 14 Issue 1, p152-163. 12p.
Database: Academic Search Ultimate
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ISSN:21638306
DOI:10.1002/psp4.13254