Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.
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| Title: | Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer. |
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| Authors: | Shang, Yanguo1 (AUTHOR), Pang, Miaomiao1 (AUTHOR), Fu, Shengnan2 (AUTHOR), Fei, Wenjuan1 (AUTHOR), Chen, Boxuan1 (AUTHOR), Zhang, Yaoyao1,3 (AUTHOR) zhangyaoyaogulou@163.com, Wang, Jinxin1,2 (AUTHOR) jinxinwang@163.com, Shen, Tao1 (AUTHOR) shentao@njtech.edu |
| Source: | European Journal of Medicinal Chemistry. May2025, Vol. 289, pN.PAG-N.PAG. 1p. |
| Database: | Academic Search Ultimate |
| ISSN: | 02235234 |
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| DOI: | 10.1016/j.ejmech.2025.117391 |
