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Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.

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Title: Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.
Authors: Shang, Yanguo1 (AUTHOR), Pang, Miaomiao1 (AUTHOR), Fu, Shengnan2 (AUTHOR), Fei, Wenjuan1 (AUTHOR), Chen, Boxuan1 (AUTHOR), Zhang, Yaoyao1,3 (AUTHOR) zhangyaoyaogulou@163.com, Wang, Jinxin1,2 (AUTHOR) jinxinwang@163.com, Shen, Tao1 (AUTHOR) shentao@njtech.edu
Source: European Journal of Medicinal Chemistry. May2025, Vol. 289, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
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DbLabel: Academic Search Ultimate
An: 184012541
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PubTypeId: academicJournal
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  Data: Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.
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  Data: <searchLink fieldCode="AR" term="%22Shang%2C+Yanguo%22">Shang, Yanguo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pang%2C+Miaomiao%22">Pang, Miaomiao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fu%2C+Shengnan%22">Fu, Shengnan</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fei%2C+Wenjuan%22">Fei, Wenjuan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Boxuan%22">Chen, Boxuan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Yaoyao%22">Zhang, Yaoyao</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> zhangyaoyaogulou@163.com</i><br /><searchLink fieldCode="AR" term="%22Wang%2C+Jinxin%22">Wang, Jinxin</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> jinxinwang@163.com</i><br /><searchLink fieldCode="AR" term="%22Shen%2C+Tao%22">Shen, Tao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> shentao@njtech.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Medicinal+Chemistry%22">European Journal of Medicinal Chemistry</searchLink>. May2025, Vol. 289, pN.PAG-N.PAG. 1p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=184012541
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ejmech.2025.117391
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      – Code: eng
        Text: English
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        StartPage: N.PAG
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      – TitleFull: Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.
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            NameFull: Shang, Yanguo
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            NameFull: Pang, Miaomiao
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            NameFull: Fu, Shengnan
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            NameFull: Chen, Boxuan
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            – D: 05
              M: 05
              Text: May2025
              Type: published
              Y: 2025
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              Value: 289
          Titles:
            – TitleFull: European Journal of Medicinal Chemistry
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