Efficient Synthesis and Biological Evaluation of 1,4-Disubstituted 3-Cyanopyridin-2(1H)-ones as Selective Inhibitors of the Post-Acid Activity of Mammalian 20S Proteasomes.

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Title: Efficient Synthesis and Biological Evaluation of 1,4-Disubstituted 3-Cyanopyridin-2(1H)-ones as Selective Inhibitors of the Post-Acid Activity of Mammalian 20S Proteasomes.
Authors: Karapetyan, L. V.1 (AUTHOR) lkarapetyan@ysu.am, Tokmajyan, G. G.1 (AUTHOR), Melikyan, G. S.1 (AUTHOR), Bouvier-Durand, M.2 (AUTHOR), Reboud-Ravaux, M.2 (AUTHOR), Pham, T. H.2 (AUTHOR)
Source: Russian Journal of Organic Chemistry. Mar2025, Vol. 61 Issue 3, p449-455. 7p.
Database: Academic Search Ultimate
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ISSN:10704280
DOI:10.1134/S107042802460373X