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Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor.

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Bibliographic Details
Title: Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor.
Authors: Throner, Scott1 (AUTHOR), Feng, Tianshu1 (AUTHOR), Andersen, Jannik N.1 (AUTHOR), Bandi, Madhavi1 (AUTHOR), Engel, Justin L.1 (AUTHOR), Gong, Shanzhong1 (AUTHOR), Gotur, Deepali1 (AUTHOR), Gu, Lina1 (AUTHOR), Huang, Alan1 (AUTHOR), Lazarides, Katherine1 (AUTHOR), Maxwell, John P.1 (AUTHOR), McCarren, Patrick1 (AUTHOR), McMillan, Brian J.1 (AUTHOR), Pham, Truc V.1 (AUTHOR), Simoneau, Antoine1 (AUTHOR), Tsai, Alice1 (AUTHOR), Whittington, Douglas A.1 (AUTHOR), Wilker, Erik1 (AUTHOR), Zhang, Minjie1 (AUTHOR), Zhang, Wenhai1 (AUTHOR)
Source: Bioorganic & Medicinal Chemistry Letters. Aug2025, Vol. 124, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
Description
ISSN:0960894X
DOI:10.1016/j.bmcl.2025.130262