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Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1C71G ALS mouse model.

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Title: Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1C71G ALS mouse model.
Authors: Hawley, Zachary C. E.1 (AUTHOR), Li, Xueying1 (AUTHOR), Bodnar, Dora1 (AUTHOR), Gu, Yuanzheng1 (AUTHOR), Luo, Yi1 (AUTHOR), Ferretti, Daniel1 (AUTHOR), Sheehy, Adam1 (AUTHOR), Driscoll, Rachelle1 (AUTHOR), Zavodszky, Maria I.1 (AUTHOR), Cao, Shaolong1 (AUTHOR), Isaza, Isabel1 (AUTHOR), Jandreski, Luke1 (AUTHOR), Liu, Yuqing1 (AUTHOR), Carlile, Thomas1 (AUTHOR), Lo, Shih-Ching1 (AUTHOR), Grimard, Anna1 (AUTHOR), Bourque, Shawn1 (AUTHOR), Utturkar, Aditya1 (AUTHOR), Desmarais, Samantha1 (AUTHOR), Arnold, H. Moore1 (AUTHOR)
Source: Acta Neuropathologica Communications. 5/24/2025, Vol. 13 Issue 1, p1-22. 22p.
Database: Academic Search Ultimate
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ISSN:20515960
DOI:10.1186/s40478-025-02005-z