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Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.

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Title: Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.
Authors: Perneel, Jolien1,2 (AUTHOR), Lastra Osua, Miranda1,2 (AUTHOR), Alidadiani, Sara1,2 (AUTHOR), Peeters, Nele1,2 (AUTHOR), De Witte, Linus1,2 (AUTHOR), Heeman, Bavo1,2 (AUTHOR), Manzella, Simona1,2 (AUTHOR), De Rycke, Riet3,4,5 (AUTHOR), Brooks, Mieu6 (AUTHOR), Perkerson, Ralph B.6 (AUTHOR), Calus, Elke2,7,8 (AUTHOR), De Coster, Wouter1,2 (AUTHOR), Neumann, Manuela9,10 (AUTHOR), Mackenzie, Ian R. A.11,12,13,14 (AUTHOR), Van Dam, Debby2,7,8,15 (AUTHOR), Asselbergh, Bob1,2 (AUTHOR), Ellender, Tommas2,7 (AUTHOR), Zhou, Xiaolai6,16 (AUTHOR) zhouxiaolai@gzzoc.com, Rademakers, Rosa1,2,6 (AUTHOR) rosa.rademakers@uantwerpen.vib.be
Source: Molecular Neurodegeneration. 4/23/2025, Vol. 20 Issue 1, p1-26. 26p.
Database: Academic Search Ultimate
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Description
ISSN:17501326
DOI:10.1186/s13024-025-00831-2