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Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species.

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Title: Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species.
Authors: Zhu, Man1,2 (AUTHOR), Ma, Meng2 (AUTHOR), Luo, Lunan2 (AUTHOR), Li, Feiyang2 (AUTHOR), Zheng, Jiashun3 (AUTHOR), Pan, Yan2 (AUTHOR), Yang, Lu2 (AUTHOR), Xiao, Ying2 (AUTHOR), Wang, Ziyan2 (AUTHOR), Xian, Bo2 (AUTHOR) xianbo@uestc.edu.cn, Zheng, Yi1,2 (AUTHOR) yi_zheng@uestc.edu.cn, Li, Hao3 (AUTHOR) haoli@genome.ucsf.edu, Yang, Jing1,2 (AUTHOR) yangjing1977@uestc.edu.cn
Source: Aging Cell. Jun2025, Vol. 24 Issue 6, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:14749718
DOI:10.1111/acel.70010