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Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.

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Title: Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.
Authors: Hüsken, Saskia1 (AUTHOR), Röder, Annika2 (AUTHOR), Ptok, Johannes3 (AUTHOR), Meyer, Anne E.1 (AUTHOR), Georg, Mats4 (AUTHOR), Schwarz, Yannick1 (AUTHOR), Roos, Christian5 (AUTHOR), Mätz-Rensing, Kerstin5 (AUTHOR), Hutter, Michael C.6 (AUTHOR), Floss, Doreen M.7 (AUTHOR), Rettie, Allan E.8 (AUTHOR), Girhard, Marco2 (AUTHOR), Hanenberg, Helmut1,9 (AUTHOR), Wiek, Constanze1 (AUTHOR) Constanze.wiek@med.uni-duesseldorf.de
Source: PLoS Genetics. 6/27/2025, Vol. 21 Issue 6, p1-28. 28p.
Database: Academic Search Ultimate
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ISSN:15537390
DOI:10.1371/journal.pgen.1011750