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Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors.

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Title: Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors.
Authors: Hodder, Anthony N.1,2 (AUTHOR), Sleebs, Brad E.1,2 (AUTHOR), Adams, Greg3 (AUTHOR), Rezazadeh, Sina3 (AUTHOR), Ngo, Anna1,2 (AUTHOR), Jarman, Kate1,2 (AUTHOR), Scally, Stephen1,2 (AUTHOR), Czabotar, Peter1,2 (AUTHOR), Wang, Hongwu3 (AUTHOR), McCauley, John A.3 (AUTHOR), Olsen, David B.3 (AUTHOR), Cowman, Alan F.1,2 (AUTHOR) cowman@wehi.edu.au
Source: FEBS Journal. Jun2025, Vol. 292 Issue 11, p2843-2864. 22p.
Database: Academic Search Ultimate
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ISSN:1742464X
DOI:10.1111/febs.70038