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The main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII.

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Title: The main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII.
Authors: Pagotto, Anna1,2 (AUTHOR), Uliana, Federico3,4 (AUTHOR), Cavedon, Elena1 (AUTHOR), Nordio, Giulia1 (AUTHOR), Pierangelini, Andrea1 (AUTHOR), Acquasaliente, Laura1 (AUTHOR), Macchia, Maria Ludovica5 (AUTHOR), Bellanda, Massimo5 (AUTHOR), Gatto, Barbara1 (AUTHOR), De Silvestro, Giustina6 (AUTHOR), Marson, Piero6 (AUTHOR), Gregori, Dario7 (AUTHOR), Simioni, Paolo8 (AUTHOR), Picotti, Paola2 (AUTHOR), De Filippis, Vincenzo1 (AUTHOR) vincenzo.defilippis@unipd.it
Source: Communications Biology. 8/1/2025, Vol. 8 Issue 1, p1-16. 16p.
Database: Academic Search Ultimate
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ISSN:23993642
DOI:10.1038/s42003-025-08570-2