Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis.

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Title: Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis.
Authors: Hirano, Yudai1 (AUTHOR), Miyawaki, Satoru1 (AUTHOR) smiya-nsu@m.u-tokyo.ac.jp, Sakai, Yu1 (AUTHOR), Teranishi, Yu1 (AUTHOR), Umekawa, Motoyuki1 (AUTHOR), Hirata, Takeru1 (AUTHOR), Ogawa, Shotaro1 (AUTHOR), Komura, Daisuke2 (AUTHOR), Katoh, Hiroto2 (AUTHOR), Ikemura, Masako3 (AUTHOR), Koizumi, Satoshi1 (AUTHOR), Ono, Hideaki1 (AUTHOR), Ushiku, Tetsuo3 (AUTHOR), Ishikawa, Shumpei2 (AUTHOR), Saito, Nobuhito1 (AUTHOR)
Source: Acta Neuropathologica Communications. 8/7/2025, Vol. 13 Issue 1, p1-10. 10p.
Database: Academic Search Ultimate
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ISSN:20515960
DOI:10.1186/s40478-025-02083-z