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JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer.

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Title: JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer.
Authors: Alexandrou, Sarah1,2 (AUTHOR), Lee, Christine S.1 (AUTHOR), Fernandez, Kristine J.1 (AUTHOR), Wiharja, Celine E.1 (AUTHOR), Eshraghi, Leila1,2 (AUTHOR), Reeves, John1 (AUTHOR), Reed, Daniel A.1,2 (AUTHOR), Portman, Neil1,2 (AUTHOR), Phan, Zoe1,2 (AUTHOR), Milioli, Heloisa H.1,2 (AUTHOR), Nikolic, Iva3 (AUTHOR), Cadell, Antonia L.1,2 (AUTHOR), Croucher, David R.1,2 (AUTHOR), Simpson, Kaylene J.3,4 (AUTHOR), Lim, Elgene1,2 (AUTHOR), Hickey, Theresa E.5 (AUTHOR), Millar, Ewan K. A.6,7 (AUTHOR), Alves, Carla L.8 (AUTHOR), Ditzel, Henrik J.8,9 (AUTHOR), Caldon, C. Elizabeth1,2 (AUTHOR) l.caldon@garvan.org.au
Source: Journal of Experimental & Clinical Cancer Research (17569966). 8/19/2025, Vol. 44 Issue 1, p1-24. 24p.
Database: Academic Search Ultimate
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ISSN:17569966
DOI:10.1186/s13046-025-03466-9