Physiologically based pharmacokinetic modelling to predict artemether and lumefantrine exposure in neonates weighing less than 5 kg treated with artemether–lumefantrine to supplement the clinical data from the CALINA study.

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Title: Physiologically based pharmacokinetic modelling to predict artemether and lumefantrine exposure in neonates weighing less than 5 kg treated with artemether–lumefantrine to supplement the clinical data from the CALINA study.
Authors: Gu, Helen1 (AUTHOR) helen.gu@novartis.com, Abla, Nada2 (AUTHOR), Venishetty, Vinay Kumar3 (AUTHOR), Schoeberl, Birgit4 (AUTHOR), Zack, Julia1 (AUTHOR), Einolf, Heidi J.1 (AUTHOR)
Source: Tropical Medicine & Health. 8/25/2025, Vol. 53 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:13488945
DOI:10.1186/s41182-025-00790-w