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Clinical Utility and Cost‐Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine‐Induced Myelosuppression: A Genotype‐First Reverse Phenotyping Cohort Study Within the UK NIHR Inflammatory Bowel Disease Bioresource

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Title: Clinical Utility and Cost‐Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine‐Induced Myelosuppression: A Genotype‐First Reverse Phenotyping Cohort Study Within the UK NIHR Inflammatory Bowel Disease Bioresource
Authors: Roberts, Christopher1,2 (AUTHOR), Peters, Jaime3 (AUTHOR), Sazonvos, Aleksejs4 (AUTHOR), Goodman, Neil5 (AUTHOR), Sharip, Mohmmed6,7 (AUTHOR), Smith, Rebecca1,2 (AUTHOR), Bishara, Maria1,2 (AUTHOR), Bewshea, Claire1 (AUTHOR), Lin, Simeng1 (AUTHOR), Chanchlani, Neil1 (AUTHOR), Hodges, Phoebe1 (AUTHOR), Badrulhisham, Fakhirah1 (AUTHOR), Saifuddin, Aamir8 (AUTHOR), Carlson, Sean9 (AUTHOR), Centritto, Andrea10 (AUTHOR), Marley, Alexandra11 (AUTHOR), Saad, Muhammad11 (AUTHOR), Sethi‐Aora, Karishma12 (AUTHOR), White, Laura8 (AUTHOR), Abdelmeguid, Alaa13 (AUTHOR)
Source: Alimentary Pharmacology & Therapeutics. Sep2025, Vol. 62 Issue 6, p630-645. 16p.
Database: Academic Search Ultimate
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ISSN:02692813
DOI:10.1111/apt.70232