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Low-dose temozolomide selectively increases glioblastoma's vascular permeability, tumor microenvironment penetration and the killing potential of systemic actinium-225 α-particle dendrimer-radioconjugates improving treatment efficacy.

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Title: Low-dose temozolomide selectively increases glioblastoma's vascular permeability, tumor microenvironment penetration and the killing potential of systemic actinium-225 α-particle dendrimer-radioconjugates improving treatment efficacy.
Authors: Nair, Rajiv Ranjit1 (AUTHOR), Sarkar, Aira1 (AUTHOR), Hariharan, Pooja1 (AUTHOR), Gabrielson, Kathleen L.2 (AUTHOR), Wu, Tony3 (AUTHOR), Liu, Chang3 (AUTHOR), Sharma, Anjali3 (AUTHOR), Liyanage, Wathsala3 (AUTHOR), Bhujwalla, Zaver M.4 (AUTHOR), Vidaver, Marie-France Penet4 (AUTHOR), Kannan, Rangaramanujam M.3 (AUTHOR), Sofou, Stavroula1,5,6 (AUTHOR) ssofou1@jhu.edu
Source: European Journal of Nuclear Medicine & Molecular Imaging. Sep2025, Vol. 52 Issue 11, p4308-4319. 12p.
Database: Academic Search Ultimate
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ISSN:16197070
DOI:10.1007/s00259-025-07332-w