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A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

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Title: A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.
Authors: Weller, Caroline1, Burnett, G. Leslie1, Jiang, Lingyan1, Chakraborty, Sujata1, Zhang, Dongyu1, Vita, Nicole A.1, Dilly, Julien2, Kim, Eejung2, Maldonato, Benjamin1, Seamon, Kyle1, Eilerts, Diane F.1, Milin, Anthony1, Marquez, Abby1, Spradlin, Jessica1, Helland, Ciara1, Gould, Andrea1, Ziv, Tamar Bar1, Dinh, Phuong1, Steele, Shelby L.1, Wang, Zhican1
Source: Science. 7/24/2025, Vol. 389 Issue 6758, p1-14. 14p.
Database: Academic Search Ultimate
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ISSN:00368075
DOI:10.1126/science.ads0239