View in EDS HTML Full Text PDF Full Text

A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

Saved in:
Bibliographic Details
Title: A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.
Authors: Weller, Caroline1, Burnett, G. Leslie1, Jiang, Lingyan1, Chakraborty, Sujata1, Zhang, Dongyu1, Vita, Nicole A.1, Dilly, Julien2, Kim, Eejung2, Maldonato, Benjamin1, Seamon, Kyle1, Eilerts, Diane F.1, Milin, Anthony1, Marquez, Abby1, Spradlin, Jessica1, Helland, Ciara1, Gould, Andrea1, Ziv, Tamar Bar1, Dinh, Phuong1, Steele, Shelby L.1, Wang, Zhican1
Source: Science. 7/24/2025, Vol. 389 Issue 6758, p1-14. 14p.
Database: Academic Search Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: asn
DbLabel: Academic Search Ultimate
An: 188103343
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A neomorphic protein interface catalyzes covalent inhibition of RAS<superscript>G12D</superscript> aspartic acid in tumors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Weller%2C+Caroline%22">Weller, Caroline</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Burnett%2C+G%2E+Leslie%22">Burnett, G. Leslie</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jiang%2C+Lingyan%22">Jiang, Lingyan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Chakraborty%2C+Sujata%22">Chakraborty, Sujata</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Dongyu%22">Zhang, Dongyu</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Vita%2C+Nicole+A%2E%22">Vita, Nicole A.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dilly%2C+Julien%22">Dilly, Julien</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kim%2C+Eejung%22">Kim, Eejung</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Maldonato%2C+Benjamin%22">Maldonato, Benjamin</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Seamon%2C+Kyle%22">Seamon, Kyle</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Eilerts%2C+Diane+F%2E%22">Eilerts, Diane F.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Milin%2C+Anthony%22">Milin, Anthony</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Marquez%2C+Abby%22">Marquez, Abby</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Spradlin%2C+Jessica%22">Spradlin, Jessica</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Helland%2C+Ciara%22">Helland, Ciara</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Gould%2C+Andrea%22">Gould, Andrea</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ziv%2C+Tamar+Bar%22">Ziv, Tamar Bar</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dinh%2C+Phuong%22">Dinh, Phuong</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Steele%2C+Shelby+L%2E%22">Steele, Shelby L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Wang%2C+Zhican%22">Wang, Zhican</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Science%22">Science</searchLink>. 7/24/2025, Vol. 389 Issue 6758, p1-14. 14p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=188103343
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/science.ads0239
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 14
        StartPage: 1
    Titles:
      – TitleFull: A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Weller, Caroline
      – PersonEntity:
          Name:
            NameFull: Burnett, G. Leslie
      – PersonEntity:
          Name:
            NameFull: Jiang, Lingyan
      – PersonEntity:
          Name:
            NameFull: Chakraborty, Sujata
      – PersonEntity:
          Name:
            NameFull: Zhang, Dongyu
      – PersonEntity:
          Name:
            NameFull: Vita, Nicole A.
      – PersonEntity:
          Name:
            NameFull: Dilly, Julien
      – PersonEntity:
          Name:
            NameFull: Kim, Eejung
      – PersonEntity:
          Name:
            NameFull: Maldonato, Benjamin
      – PersonEntity:
          Name:
            NameFull: Seamon, Kyle
      – PersonEntity:
          Name:
            NameFull: Eilerts, Diane F.
      – PersonEntity:
          Name:
            NameFull: Milin, Anthony
      – PersonEntity:
          Name:
            NameFull: Marquez, Abby
      – PersonEntity:
          Name:
            NameFull: Spradlin, Jessica
      – PersonEntity:
          Name:
            NameFull: Helland, Ciara
      – PersonEntity:
          Name:
            NameFull: Gould, Andrea
      – PersonEntity:
          Name:
            NameFull: Ziv, Tamar Bar
      – PersonEntity:
          Name:
            NameFull: Dinh, Phuong
      – PersonEntity:
          Name:
            NameFull: Steele, Shelby L.
      – PersonEntity:
          Name:
            NameFull: Wang, Zhican
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 07
              Text: 7/24/2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 00368075
          Numbering:
            – Type: volume
              Value: 389
            – Type: issue
              Value: 6758
          Titles:
            – TitleFull: Science
              Type: main
ResultId 1