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Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling.

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Title: Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling.
Authors: Yang, Yuanheng1,2, Hao, Cong1, Jiao, Tingying3,4, Yang, Zidan5,6,7, Li, Hui1,5,6, Zhang, Yuqing8,9, Zhang, Weiya10,11, Doherty, Michael10,11, Sun, Chuying12, Yang, Tuo5,6,13, Li, Jiatian1, Wu, Jing5,6, Zhang, Mengjiao12, Wang, Yilun1,5,6, Xie, Dongxing1,5,6, Wang, Tingjian5,6,14, Wang, Ning1,5,6, Huang, Xi15,16, Li, Changjun5,6,17, Gonzalez, Frank J.18
Source: Science. 4/4/2025, Vol. 388 Issue 6742, p1-13. 13p.
Database: Academic Search Ultimate
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ISSN:00368075
DOI:10.1126/science.adt0548