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Facilitated α-synuclein oligomer sharing among glial cells by a centrally acting connexin inhibitor attenuates a rapidly progressive multiple system atrophy-cerebellar type model by reducing the neuronal α-synuclein burden.

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Title: Facilitated α-synuclein oligomer sharing among glial cells by a centrally acting connexin inhibitor attenuates a rapidly progressive multiple system atrophy-cerebellar type model by reducing the neuronal α-synuclein burden.
Authors: Harada, Masaya1,2 (AUTHOR), Masaki, Katsuhisa1 (AUTHOR), Tanaka, Tatsunori1,3 (AUTHOR), Sekiya, Hiroaki4 (AUTHOR), Matsuse, Dai1 (AUTHOR), Yamaguchi, Hiroo1,5 (AUTHOR), Nishimura, Yuji1 (AUTHOR), Takase, Ezgi Ozdemir1 (AUTHOR), Tanaka, Eizo1 (AUTHOR), Kira, Yuu-ichi1 (AUTHOR), Fujishima, Kei1 (AUTHOR), Matsuo, Eriko1 (AUTHOR), Yamasaki, Ryo1 (AUTHOR), Dickson, Dennis W.4 (AUTHOR), Suzumura, Akio6 (AUTHOR), Taniwaki, Takayuki2 (AUTHOR), Hoshino, Tomoaki2 (AUTHOR), Isobe, Noriko1 (AUTHOR), Takeuchi, Hideyuki7,8 (AUTHOR), Kira, Jun-ichi1,9 (AUTHOR) kira.jun-ichi.386@m.kyushu-u.ac.jp
Source: Acta Neuropathologica Communications. 9/24/2025, Vol. 13 Issue 1, p1-29. 29p.
Database: Academic Search Ultimate
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ISSN:20515960
DOI:10.1186/s40478-025-02116-7