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Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.

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Bibliographic Details
Title: Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.
Authors: Alicea Pauneto, Coral del Mar1,2 (AUTHOR), Riesenberg, Brian P.1 (AUTHOR), Gandy, Evelyn J.1 (AUTHOR), Kennedy, Andrew S.1,3 (AUTHOR), Clutton, Genevieve T.1 (AUTHOR), Hem, Jessica W.1,4 (AUTHOR), Hurst, Katie E.1 (AUTHOR), Hunt, Elizabeth G.1,3 (AUTHOR), Green, Jarred M.1,4 (AUTHOR), Miller, Brian C.1,5 (AUTHOR), Angus, Steven P.1,2 (AUTHOR), Johnson, Gary L.1,2 (AUTHOR), Esther, Robert J.1,6 (AUTHOR), Guerriero, Jennifer L.7,8,9,10 (AUTHOR), Gao, Peng11 (AUTHOR), Soto-Pantoja, David R.12 (AUTHOR), Ferris, Robert L.1,4,5 (AUTHOR), Modliszewski, Jennifer L.1 (AUTHOR), Coleman, Michael F.13 (AUTHOR), Chung, H. Kay1,3 (AUTHOR)
Source: Immunity (10747613). Oct2025, Vol. 58 Issue 10, p2489-25250. 22762p.
Database: Academic Search Ultimate
Description
ISSN:10747613
DOI:10.1016/j.immuni.2025.09.003