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Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.

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Title: Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.
Authors: Alicea Pauneto, Coral del Mar1,2 (AUTHOR), Riesenberg, Brian P.1 (AUTHOR), Gandy, Evelyn J.1 (AUTHOR), Kennedy, Andrew S.1,3 (AUTHOR), Clutton, Genevieve T.1 (AUTHOR), Hem, Jessica W.1,4 (AUTHOR), Hurst, Katie E.1 (AUTHOR), Hunt, Elizabeth G.1,3 (AUTHOR), Green, Jarred M.1,4 (AUTHOR), Miller, Brian C.1,5 (AUTHOR), Angus, Steven P.1,2 (AUTHOR), Johnson, Gary L.1,2 (AUTHOR), Esther, Robert J.1,6 (AUTHOR), Guerriero, Jennifer L.7,8,9,10 (AUTHOR), Gao, Peng11 (AUTHOR), Soto-Pantoja, David R.12 (AUTHOR), Ferris, Robert L.1,4,5 (AUTHOR), Modliszewski, Jennifer L.1 (AUTHOR), Coleman, Michael F.13 (AUTHOR), Chung, H. Kay1,3 (AUTHOR)
Source: Immunity (10747613). Oct2025, Vol. 58 Issue 10, p2489-25250. 22762p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22Immunity+%2810747613%29%22">Immunity (10747613)</searchLink>. Oct2025, Vol. 58 Issue 10, p2489-25250. 22762p.
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        Value: 10.1016/j.immuni.2025.09.003
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        Text: English
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              Text: Oct2025
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