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GFRAL-Fc disarms GDF15 to reprogram tumor immunity and amplify PD-1 efficacy in hepatocellular carcinoma.

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Title: GFRAL-Fc disarms GDF15 to reprogram tumor immunity and amplify PD-1 efficacy in hepatocellular carcinoma.
Authors: Shi, Gege1 (AUTHOR) wshige@163.com, Zhang, Wangqian1 (AUTHOR) zhangwangqianzwq@163.com, Xie, Fei1 (AUTHOR) 2277858548@qq.com, Shi, Jiaxin1 (AUTHOR) 1821545272@qq.com, Yan, Minghui1 (AUTHOR) 19991557416@163.com, He, Lei1 (AUTHOR) heleilei@fmmu.edu.cn, Li, Zhaozhao1 (AUTHOR) L18391294396@163.com, Xiao, Yang1 (AUTHOR) xiaoyangbiu@163.com, Yu, Duo1 (AUTHOR) yuduo8579@163.co, Cao, Haiyan1 (AUTHOR) caohaiyan7@163.com, Du, Haichen1 (AUTHOR) DHC376741013@outlook.com, Qiu, Yueyuan1 (AUTHOR) qiuyueyuan123@163.com, Zhang, Kuo1 (AUTHOR) justy1985@126.com, Wang, Shuning1 (AUTHOR) shuningwang999@163.com, Li, Meng1 (AUTHOR) limeng@fmmu.edu.cn, Zhang, Jieyu1 (AUTHOR) zjieyu@fmmu.edu.cn, Wang, Zhaowei1 (AUTHOR) w1993zw@fmmu.edu.cn
Source: Cell Communication & Signaling. 10/15/2025, Vol. 23 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:1478811X
DOI:10.1186/s12964-025-02427-1