The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration.
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| Title: | The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration. |
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| Authors: | Kurniawan, Henry1 (AUTHOR) henry.kurniawan@uni.lu, Nickels, Sarah L.1 (AUTHOR), Zagare, Alise1 (AUTHOR), Zuccoli, Elisa1 (AUTHOR), Rosety, Isabel1 (AUTHOR), Gomez-Giro, Gemma1 (AUTHOR), Glaab, Enrico2 (AUTHOR), Schwamborn, Jens C.1 (AUTHOR) Jens.Schwamborn@uni.lu |
| Source: | Journal of Neuroinflammation. 10/27/2025, Vol. 22 Issue 1, p1-17. 17p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 17422094 |
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| DOI: | 10.1186/s12974-025-03577-2 |
