Challenges and limitations of chimeric antigen receptor T-cell therapies in solid tumors: why are approvals restricted to hematologic malignancies?

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Title: Challenges and limitations of chimeric antigen receptor T-cell therapies in solid tumors: why are approvals restricted to hematologic malignancies?
Authors: Vo, Manh-Cuong1,2,3 (AUTHOR), Tran, Van-Dinh-Huan2 (AUTHOR), Nguyen, Van-Tan2 (AUTHOR), Ruzimurodov, Nodirjon4 (AUTHOR), Trung, Dung Tran5 (AUTHOR), Kim, Sang Ki2,3,6 (AUTHOR), Jung, Sung-Hoon2,7 (AUTHOR) shglory@hanmail.net, Lee, Je-Jung2,3,7 (AUTHOR) drjejung@chonnam.ac.kr
Source: Journal of Hematology & Oncology. 10/27/2025, Vol. 18 Issue 1, p1-31. 31p.
Database: Academic Search Ultimate
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ISSN:17568722
DOI:10.1186/s13045-025-01744-9