The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice.
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| Title: | The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice. |
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| Authors: | Colunga-Biancatelli, Ruben M. L.1,2 (AUTHOR) rcolunga@odu.edu, Solopov, Pavel A.1 (AUTHOR), Woodson, Caitlin M.3,4 (AUTHOR), Allen, Irving Coy3,4 (AUTHOR), Akhrymuk, Ivan3,4 (AUTHOR), Akhrymuk, Maryna3,4 (AUTHOR), Heath, Brittany N.3,4 (AUTHOR), Ivester, Hannah M.5 (AUTHOR), Day, Tierney1 (AUTHOR), Austin, Dan E.6 (AUTHOR), Kehn-Hall, Kylene3,4 (AUTHOR), Lazo, John S.7,8 (AUTHOR), Sharlow, Elizabeth R.7,8 (AUTHOR), Catravas, John D.1,2,9 (AUTHOR) |
| Source: | Respiratory Research. 10/28/2025, Vol. 26 Issue 1, p1-13. 13p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 14659921 |
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| DOI: | 10.1186/s12931-025-03349-9 |
