The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice.
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| Title: | The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice. |
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| Authors: | Colunga-Biancatelli, Ruben M. L.1,2 (AUTHOR) rcolunga@odu.edu, Solopov, Pavel A.1 (AUTHOR), Woodson, Caitlin M.3,4 (AUTHOR), Allen, Irving Coy3,4 (AUTHOR), Akhrymuk, Ivan3,4 (AUTHOR), Akhrymuk, Maryna3,4 (AUTHOR), Heath, Brittany N.3,4 (AUTHOR), Ivester, Hannah M.5 (AUTHOR), Day, Tierney1 (AUTHOR), Austin, Dan E.6 (AUTHOR), Kehn-Hall, Kylene3,4 (AUTHOR), Lazo, John S.7,8 (AUTHOR), Sharlow, Elizabeth R.7,8 (AUTHOR), Catravas, John D.1,2,9 (AUTHOR) |
| Source: | Respiratory Research. 10/28/2025, Vol. 26 Issue 1, p1-13. 13p. |
| Database: | Academic Search Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 188948382 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Colunga-Biancatelli%2C+Ruben+M%2E+L%2E%22">Colunga-Biancatelli, Ruben M. L.</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> rcolunga@odu.edu</i><br /><searchLink fieldCode="AR" term="%22Solopov%2C+Pavel+A%2E%22">Solopov, Pavel A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Woodson%2C+Caitlin+M%2E%22">Woodson, Caitlin M.</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Allen%2C+Irving+Coy%22">Allen, Irving Coy</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Akhrymuk%2C+Ivan%22">Akhrymuk, Ivan</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Akhrymuk%2C+Maryna%22">Akhrymuk, Maryna</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heath%2C+Brittany+N%2E%22">Heath, Brittany N.</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ivester%2C+Hannah+M%2E%22">Ivester, Hannah M.</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Day%2C+Tierney%22">Day, Tierney</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Austin%2C+Dan+E%2E%22">Austin, Dan E.</searchLink><relatesTo>6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kehn-Hall%2C+Kylene%22">Kehn-Hall, Kylene</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lazo%2C+John+S%2E%22">Lazo, John S.</searchLink><relatesTo>7,8</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sharlow%2C+Elizabeth+R%2E%22">Sharlow, Elizabeth R.</searchLink><relatesTo>7,8</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Catravas%2C+John+D%2E%22">Catravas, John D.</searchLink><relatesTo>1,2,9</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Respiratory+Research%22">Respiratory Research</searchLink>. 10/28/2025, Vol. 26 Issue 1, p1-13. 13p. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=188948382 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12931-025-03349-9 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Titles: – TitleFull: The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Colunga-Biancatelli, Ruben M. L. – PersonEntity: Name: NameFull: Solopov, Pavel A. – PersonEntity: Name: NameFull: Woodson, Caitlin M. – PersonEntity: Name: NameFull: Allen, Irving Coy – PersonEntity: Name: NameFull: Akhrymuk, Ivan – PersonEntity: Name: NameFull: Akhrymuk, Maryna – PersonEntity: Name: NameFull: Heath, Brittany N. – PersonEntity: Name: NameFull: Ivester, Hannah M. – PersonEntity: Name: NameFull: Day, Tierney – PersonEntity: Name: NameFull: Austin, Dan E. – PersonEntity: Name: NameFull: Kehn-Hall, Kylene – PersonEntity: Name: NameFull: Lazo, John S. – PersonEntity: Name: NameFull: Sharlow, Elizabeth R. – PersonEntity: Name: NameFull: Catravas, John D. IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 10 Text: 10/28/2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 14659921 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: Respiratory Research Type: main |
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