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POINTER: study protocol for a phase 2b, randomised, placebo-controlled, double-blind, parallel group dose-finding clinical study to evaluate the efficacy of RMC-035 on renal function and safety, in participants at high risk for kidney injury, following open-chest cardiac surgery

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Title: POINTER: study protocol for a phase 2b, randomised, placebo-controlled, double-blind, parallel group dose-finding clinical study to evaluate the efficacy of RMC-035 on renal function and safety, in participants at high risk for kidney injury, following open-chest cardiac surgery
Authors: Zarbock, Alexander1 (AUTHOR) zarbock@uni-muenster.de, Strauss, Christian1 (AUTHOR), Laflamme, Maxime2 (AUTHOR), Myjavec, Andrej3 (AUTHOR), Böhm, Johannes4 (AUTHOR), Burkert, Jan5 (AUTHOR), Mazer, C. David6 (AUTHOR), de Varennes, Benoit7 (AUTHOR), Iglesias, Antonino Ginel8 (AUTHOR), Matschke, Klaus9 (AUTHOR), Larsson, Tobias E.10 (AUTHOR), Reusch, Michael10 (AUTHOR)
Source: Trials. 10/28/2025, Vol. 26 Issue 1, p1-16. 16p.
Database: Academic Search Ultimate
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ISSN:17456215
DOI:10.1186/s13063-025-09124-x