Tumor mutational burden modulates the prognostic effect of RAS mutations in metastatic colon cancer: mechanistic insights and genotype-phenotype correlations.

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Title: Tumor mutational burden modulates the prognostic effect of RAS mutations in metastatic colon cancer: mechanistic insights and genotype-phenotype correlations.
Authors: Ianniello, Monica1 (AUTHOR), Ottaiano, Alessandro2 (AUTHOR) a.ottaiano@istitutotumori.na.it, Bocchetti, Marco3,4 (AUTHOR), Ruggiero, Raffaella1 (AUTHOR), Santorsola, Mariachiara2 (AUTHOR), Sirica, Roberto1 (AUTHOR), Caraglia, Francesco5 (AUTHOR), Ceccarelli, Anna6 (AUTHOR), Toscano, Enrica7 (AUTHOR), Picone, Carmine2 (AUTHOR), Ciappina, Giuliana7 (AUTHOR), Cossu, Alessia Maria5 (AUTHOR), Petrillo, Nadia1 (AUTHOR), Fico, Antonio1 (AUTHOR), Circelli, Luisa1 (AUTHOR), Sabbatino, Francesco8 (AUTHOR), Barone, Antonio1 (AUTHOR), Sperlongano, Rossella5 (AUTHOR), Berretta, Massimiliano9 (AUTHOR), Caraglia, Michele5 (AUTHOR)
Source: Journal of Translational Medicine. 11/5/2025, Vol. 23 Issue 1, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:14795876
DOI:10.1186/s12967-025-07273-w