The novel sphingolipids cP1P and P1P attenuate neuroinflammation and enhance S1PR1/Akt/mTOR signaling to mitigate cognitive decline in an Alzheimer's disease mouse model.

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Title: The novel sphingolipids cP1P and P1P attenuate neuroinflammation and enhance S1PR1/Akt/mTOR signaling to mitigate cognitive decline in an Alzheimer's disease mouse model.
Authors: Choe, Kyonghwan1,2 (AUTHOR) k.choe@gnu.ac.kr, Ahmad, Riaz1 (AUTHOR) riazk0499@gnu.ac.kr, Kang, Min Hwa1 (AUTHOR) kmh1020@gnu.ac.kr, Lee, Hyeon Jin1 (AUTHOR) lhj4912@gnu.ac.kr, Ahmad, Sareer1 (AUTHOR) sareerkhan2020@gnu.ac.kr, Park, Tae Ju3 (AUTHOR) taeju.park@einsteinmed.edu, Kim, Myeong Ok1,4 (AUTHOR) mokim@gnu.ac.kr
Source: Cell Communication & Signaling. 11/7/2025, Vol. 23 Issue 1, p1-19. 19p.
Database: Academic Search Ultimate
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ISSN:1478811X
DOI:10.1186/s12964-025-02485-5