GX15-070 enhances niraparib efficacy in ovarian cancer by promoting a shift in Mcl1-mediated DNA repair pathway from HR to NHEJ.

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Title: GX15-070 enhances niraparib efficacy in ovarian cancer by promoting a shift in Mcl1-mediated DNA repair pathway from HR to NHEJ.
Authors: Sheng, Jia-Jia1,2 (AUTHOR), He, Yan1 (AUTHOR), Liu, Po-Wu1 (AUTHOR), Zheng, Sheng-An1,2 (AUTHOR), Wu, Nayiyuan1 (AUTHOR), Sui, Hong-Ying1 (AUTHOR) suihongying@hnca.org.cn, Cheng, Quan3 (AUTHOR) chengquan@csu.edu.cn, Li, He1,4 (AUTHOR) lihe@hnca.org.cn
Source: Journal of Translational Medicine. 11/11/2025, Vol. 23 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:14795876
DOI:10.1186/s12967-025-07284-7