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Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.

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Bibliographic Details
Title: Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.
Authors: Luu, Phuong Vu1 (AUTHOR) m303113001@tmu.edu.tw, Peng, Bo-Rong1,2 (AUTHOR), Phan, Thuy-Tien Thi3,4 (AUTHOR) m825112007@tmu.edu.tw, Nguyen, Cuong-Quoc5 (AUTHOR) ncquoc@ctu.edu.vn, Huynh, Quoc-Dung Tran4,6 (AUTHOR) d339110005@tmu.edu.tw, Pham, Ngoc-Thac7 (AUTHOR) d339112005@tmu.edu.tw, Le, Huong-Giang8 (AUTHOR) d339111003@tmu.edu.tw, Chen, Lo-Yun7 (AUTHOR) d339112001@tmu.edu.tw, Shen, Yao-An9,10,11 (AUTHOR) shen1202@tmu.edu.tw, Fan, Yu-Jui12,13 (AUTHOR) ray.yj.fan@tmu.edu.tw, Lai, Kuei-Hung1,7,14,15 (AUTHOR) kueihunglai@tmu.edu.tw
Source: Bioorganic Chemistry. Dec2025, Vol. 167, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
Description
ISSN:00452068
DOI:10.1016/j.bioorg.2025.109255