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Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.

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Title: Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.
Authors: Luu, Phuong Vu1 (AUTHOR) m303113001@tmu.edu.tw, Peng, Bo-Rong1,2 (AUTHOR), Phan, Thuy-Tien Thi3,4 (AUTHOR) m825112007@tmu.edu.tw, Nguyen, Cuong-Quoc5 (AUTHOR) ncquoc@ctu.edu.vn, Huynh, Quoc-Dung Tran4,6 (AUTHOR) d339110005@tmu.edu.tw, Pham, Ngoc-Thac7 (AUTHOR) d339112005@tmu.edu.tw, Le, Huong-Giang8 (AUTHOR) d339111003@tmu.edu.tw, Chen, Lo-Yun7 (AUTHOR) d339112001@tmu.edu.tw, Shen, Yao-An9,10,11 (AUTHOR) shen1202@tmu.edu.tw, Fan, Yu-Jui12,13 (AUTHOR) ray.yj.fan@tmu.edu.tw, Lai, Kuei-Hung1,7,14,15 (AUTHOR) kueihunglai@tmu.edu.tw
Source: Bioorganic Chemistry. Dec2025, Vol. 167, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
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DbLabel: Academic Search Ultimate
An: 189760105
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PubType: Academic Journal
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  Data: Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.
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  Data: <searchLink fieldCode="AR" term="%22Luu%2C+Phuong+Vu%22">Luu, Phuong Vu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> m303113001@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Peng%2C+Bo-Rong%22">Peng, Bo-Rong</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Phan%2C+Thuy-Tien+Thi%22">Phan, Thuy-Tien Thi</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<i> m825112007@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Nguyen%2C+Cuong-Quoc%22">Nguyen, Cuong-Quoc</searchLink><relatesTo>5</relatesTo> (AUTHOR)<i> ncquoc@ctu.edu.vn</i><br /><searchLink fieldCode="AR" term="%22Huynh%2C+Quoc-Dung+Tran%22">Huynh, Quoc-Dung Tran</searchLink><relatesTo>4,6</relatesTo> (AUTHOR)<i> d339110005@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Pham%2C+Ngoc-Thac%22">Pham, Ngoc-Thac</searchLink><relatesTo>7</relatesTo> (AUTHOR)<i> d339112005@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Le%2C+Huong-Giang%22">Le, Huong-Giang</searchLink><relatesTo>8</relatesTo> (AUTHOR)<i> d339111003@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Chen%2C+Lo-Yun%22">Chen, Lo-Yun</searchLink><relatesTo>7</relatesTo> (AUTHOR)<i> d339112001@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Shen%2C+Yao-An%22">Shen, Yao-An</searchLink><relatesTo>9,10,11</relatesTo> (AUTHOR)<i> shen1202@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Fan%2C+Yu-Jui%22">Fan, Yu-Jui</searchLink><relatesTo>12,13</relatesTo> (AUTHOR)<i> ray.yj.fan@tmu.edu.tw</i><br /><searchLink fieldCode="AR" term="%22Lai%2C+Kuei-Hung%22">Lai, Kuei-Hung</searchLink><relatesTo>1,7,14,15</relatesTo> (AUTHOR)<i> kueihunglai@tmu.edu.tw</i>
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  Data: <searchLink fieldCode="JN" term="%22Bioorganic+Chemistry%22">Bioorganic Chemistry</searchLink>. Dec2025, Vol. 167, pN.PAG-N.PAG. 1p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=189760105
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      – Type: doi
        Value: 10.1016/j.bioorg.2025.109255
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      – Code: eng
        Text: English
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      – TitleFull: Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.
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              Text: Dec2025
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